Mayo Clinic RNA Discoveries and Therapeutics Conference 2025
$85.00
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May 30 – 31 – 2025 – Internet Live Activity – Jacksonville, Florida
The Mayo Clinic RNA Discoveries and Therapeutics Conference 2025 will convene experts in the areas of RNA Biology and RNA Therapeutics Development and Application in disease areas including but not limited to neurological diseases, cancer and rare diseases. It will help identify gaps and opportunities in this field to leverage RNA therapeutics from discovery to translation to clinical trials.
Target Audience
This course is relevant for physicians and other healthcare providers specializing in oncology, neurology, rare diseases, and metabolic specialties. The content also benefits individuals involved in cancer research, neurological studies, the development of RNA-based therapeutics, and clinical trial coordinators.
Learning Objectives
Upon completion of this activity, participants should be able to:
- Review the current state of RNA therapeutics to include their discovery and translation into practice
- Assess existing approaches to the discovery of RNA targets
- Identify gaps in the development of RNA therapies for common complex and rare diseases
- Assess existing approaches to the development of novel therapies to include treatment and delivery modalities
- Identify future opportunities for development of RNA therapies in common complex and rare diseases
| FRIDAY MAY 30, 2025 | |
| 7:30AM | Registration & Breakfast |
| 8:00AM | Welcome
Kent R. Thielen, M.D. |
| 8:05AM | Mayo Clinic Research
Alfredo Quinones-Hinojosa, M.D |
| 8:10AM | Mayo Clinic RNA Program
Nilüfer Ertekin-Taner, M.D., Ph.D. |
| 8:30AM | Discovery of RNA-Targeting Compounds and Implications for Human Diseases
Blanton Tolbert, Ph.D. (University of Pennsylvania, HHMI) |
| 9:30AM | Break/Exhibit Hall |
| 9:45AM
|
Harnessing RNA Biology Towards Therapies
Haidong Dong, M.D., Ph.D. (Mayo Clinic) Jane Zhu, M.D., Ph.D. (Mayo Clinic) Jeff Coller, Ph.D. (Johns Hopkins University) Xiling Shen, Ph.D. (MD Anderson Cancer Center) |
| 10:45AM | Short talks selected from submitted abstracts |
| 11:45AM | Lunch/Exhibit Hall |
| 12:45PM | Advances in Translation of RNA Therapies to the Clinic
Keith Gagnon, Ph.D. (Wake Forest University School of Medicine) Julie Allickson, Ph.D. (Mayo Clinic) Keith Knutson, Ph.D. (Mayo Clinic) Robert DeLong, Ph.D. (Landmark Bio) |
| 1:45PM | RNA Therapeutics from Bench to Bedside: Moderna Experience
Patrick Finn, Ph.D. (Moderna) |
| 2:30PM | RNA Therapeutics: From Design to ASO Candidates
Jeff Milton (La Jolla Labs) |
| 3:00PM | Break/Exhibit Hall |
| 3:30PM | Accelerating RNA Therapies Towards the Clinic – Lessons Learned from Industry
Jay Parrish, Ph.D. (Pretzel Therapeutics) Susan Catalano, Ph.D. (Circle Biopharma) Claes Wahlestedt, M.D., Ph.D. (University of Miami) Andrew J. Geall, Ph.D. (Alliance for mRNA Medicines) Kate Broderick, Ph.D. (Maravai LifeSciences) Roberta Duncan (Arcturus Therapeutics) |
| 4:45PM | Adjourn |
| 5:00PM – 6:30PM | Reception & Poster Exhibition |
| SATURDAY MAY 31, 2025 | |
| 7:30AM | Breakfast |
| 7:55AM | Welcome
Nilüfer Ertekin-Taner, M.D., Ph.D. & Alfredo Quinones-Hinojosa, M.D. |
| 8:00AM | Clinical Translation of Therapeutic RNA Nano-vaccines for Cancer
Natalie Silver, M.D. (Cleveland Clinic) |
| 9:00AM | Break/Exhibit Hall |
| 9:15AM | Applications of RNA Therapeutics and Diagnostics in Common and Rare Diseases Ken Yamada, Ph.D. (UMass Chan Medical School)Marlen Lauffer, M.D. (Dutch Center for RNA Therapeutics)Margot Cousin, Ph.D. (Mayo Clinic) Minerva Carrasquillo, Ph.D. (Mayo Clinic) Tsuneya Ikezu, M.D., Ph.D. (Mayo Clinic) |
| 10:15AM | Short talks selected from submitted abstracts |
| 10:45AM | Industrializing the Non-Profit ASO Treatment of Nano-Rare Patients
Amy Williford, Ph.D. (n-Lorem Foundation) |
| 11:45AM | Lunch/Exhibit Hall |
| 12:45PM | Argonauts and RNA Therapies
Phillip Zamore, Ph.D. (UMass Chan School of Medicine) |
| 1:45PM | Disruption of RNA Metabolism in Neurodegeneration and Pathway to Treatments
Don W. Cleveland, Ph.D. (University of California San Diego) |
| 2:45PM | Break/Exhibit Hall |
| 3:00PM | Designing RNA Therapies-Advances and Considerations in Data Analytics
Alper Kucukural, Ph.D. (UMass Chan Medical School) Xue Wang, Ph.D. (Mayo Clinic) Yan Asmann, Ph.D. (Mayo Clinic) Richard Braatz, Ph.D. (MIT) |
| 4:00PM | Closing Remarks/Adjourn |
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